What are the types of osteogenesis imperfecta?

  • Type I: This is the mildest and most common form of OI. Type I leads to broken bones (bone fractures) or muscle weakness.
  • Type II: Babies born with Type II often can’t breathe and die young.
  • Type III: Babies often have broken bones at birth.
  • Type IV: Bones may break easily.

What are the two types of osteogenesis?

Type I (also known as classic non-deforming osteogenesis imperfecta with blue sclerae) is the mildest form of osteogenesis imperfecta. Type II (also known as perinatally lethal osteogenesis imperfecta) is the most severe.

What causes osteogenesis imperfecta Type 3?

OI type III is caused by changes ( mutations ) in the COL1A1 or COL1A2 genes and is inherited in an autosomal dominant manner. Treatment is based on the signs and symptoms present in each person.

What is the most common type of osteogenesis imperfecta?

The OI types are as follows: Type I. Mildest and most common type. About 50% of all affected children have this type.

What are the types of OI?

Here are the four main types of OI:

  • Type 1 OI. Type 1 OI is the mildest and most common form of brittle bone disease.
  • Type 2 OI. Type 2 OI is the most severe form of brittle bone disease, and it can be life-threatening.
  • Type 3 OI. Type 3 OI is also a severe form of brittle bone disease.
  • Type 4 OI.

What is Type 2 Osteogenesis Imperfecta?

OI type II is the most severe type of osteogenesis imperfecta. Affected infants often experience life-threatening complications at birth or shortly after. Infants with OI type II have low birth weight, abnormally short arms and legs and blue sclera.

What osteogenesis imperfecta means?

Osteogenesis imperfecta (OI) is an inherited (genetic) bone disorder that is present at birth. It is also known as brittle bone disease. A child born with OI may have soft bones that break (fracture) easily, bones that are not formed normally, and other problems. Signs and symptoms may range from mild to severe.

What is osteogenesis imperfecta type1?

Osteogenesis imperfecta (OI) is a group of genetic disorders that mainly affect the bones. Osteogenesis imperfecta type 1 is the mildest form of OI and is characterized by bone fractures during childhood and adolescence that often result from minor trauma. Fractures occur less frequently in adulthood.