Pathogenic organisms are of five main types: viruses, bacteria, fungi, protozoa, and worms.

What is osteoblastic and osteoclastic?

OSTEOCLASTS are large cells that dissolve the bone. They are found on the surface of the bone mineral next to the dissolving bone. OSTEOBLASTS are the cells that form new bone. They also come from the bone marrow and are related to structural cells.

What killed bacteria?

Some examples of disinfectants that can kill bacteria on surfaces include: products that contain alcohol, such as ethanol and isopropyl alcohol. household bleach.

How does osteoblasts maintain homeostasis?

Bone homeostasis is maintained by a balance between bone resorption by osteoclasts and bone formation by osteoblasts. During the processes, pro-inflammatory cytokines such as IL-1 and TNF-alpha, cause an imbalance in bone metabolism, by favoring bone resorption via the induction of RANKL and ICAM-1 on osteoblasts.

What type of pathogen is bacteria?

Bacteria are microscopic pathogens that reproduce rapidly after entering the body. They can release toxins that damage tissues and cause illness. Doctors typically prescribe antibiotics to treat bacterial infections, but some bacteria are becoming resistant to these drugs. Not all bacteria are pathogenic, though.

What is the smallest pathogen?

Viruses are the smallest common pathogen. They are so small in fact that many of them actually infect bacteria. They are different from other pathogens because they cannot reproduce on their own.

Is Lemon an antibiotic?

The bioactive compounds contained in lemon (Citrus limon) each have an antibacterial [13]. Lemon (Citrus aurantifolia) juice besides being used as an antibacterial, it is also useful as an antioxidant.

What is the difference between osteoblastic and osteolytic disease?

In osteoblastic metastases the vicious cycle observed in osteolytic disease still occurs, however, in addition to this tumour cells within bone produce osteoblast-stimulating factors comprised of bone morphogenic protein (BMP)s, epidermal growth factor (EGF)s and platelet derived growth factor (PDGF).

What is the prognosis of osteoblastic bone metastases?

Progression to overt metastases. Because osteoblastic bone metastases is characterised by increases in both bone resorption and bone formation lesions consist of weakened bone with abnormal architecture and patients with this condition are at increased risk of fracture (common in prostate) [16].

What is osteoclastic bone resorption and osteolytic lesions?

When this happens, osteoclastic bone resorption exceeds osteoblastic bone formation resulting in bone degradation and the formation of osteolytic lesions (common in breast, lung and multiple myeloma).

What is the function of osteoblasts in bone cancer?

Osteoblasts play an important role during skeletal development and remodeling by depositing and mineralizing new bone, and regulating osteoclastogenesis and bone resorption. Accumulating evidence supports that cancer cells manipulate osteoblasts to facilitate bone colonization and tumor survival and proliferation.