Even if you’re allergic to antibiotics that have sulfa, you might be able to take some other types of sulfa drugs without a reaction. Ones that may be safe to take include: Glyburide (Glynase, Diabeta), a drug for diabetes. Celecoxib (Celebrex), a nonsteroidal anti-inflammatory drug (NSAID)

Which NSAID is contraindicated in sulfa allergy?

Celecoxib, a selective cyclo-oxygenase-2 inhibitor, is a diaryl-substituted pyrazole derivative containing a sulfonamide substituent. Because of this structural component, celecoxib is contraindicated for use in patients who have demonstrated allergic reactions to sulfonamides.

Is NSAIDs a sulfa?

Other NSAIDs do not have sulfa components. The older non-selective NSAIDs might be used with a proton pump inhibitor (prilosec, prevacid, protonix, nexium) to help protect the stomach.

Is Celebrex sulfa based?

CELEBREX is a sulfonamide and both NSAIDs and sulfonamides may cause allergic type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people.

What drugs are sulfa based?

Sulfa-containing drugs include:

  • sulfonamide antibiotics, including sulfamethoxazole-trimethoprim (Bactrim, Septra) and erythromycin-sulfisoxazole (Eryzole, Pediazole)
  • some diabetes medications, such as glyburide (Diabeta, Glynase PresTabs)

Is meloxicam safe with sulfa allergy?

Official Answer. Meloxicam does contain sulfa, although not the typical sulfonamide structure which typically occurs in those with sulfa allergies. If you are experiencing unwanted side effects, the best thing is to see your doctor.

Is omeprazole a sulfa drug?

After omeprazole is released from coating, it is converted into active sulfonamide form in the acidic environment (MedicineNet, 2009). This active sulfonamide form is then form covalent bond to cysteine residues to release proton pumps.

Does Cipro have sulfa in it?

Bactrim (sulfamethoxazole and trimethoprim) is a combination of two antibiotics (a sulfa drug and a folic acid inhibitor) and Cipro (ciprofloxacin) is a quinolone antibiotic. Both drug are used to treat bacterial infections such as urinary tract infections, bronchitis and other lung infections.

Can over-the-counter NSAIDs cause ulcers?

Using over-the-counter NSAIDs for the occasional headache or achy back won’t typically cause a peptic ulcer. Rather, peptic ulcer disease is something that can occur with longer-term use of NSAIDs, especially at high doses, such as for chronic pain associated with arthritis or other inflammatory conditions. 2

What medications are safe to take for sulfa allergy?

Sulfonamide medications that may be OK. There are no diagnostic tests for sulfa allergy. However, sulfa desensitization might be an option, especially if medication containing sulfamethoxazole is needed.

What is the most important predictor of NSAIDs-induced ulcers?

A prior history of ulcers is the most important predictor of NSAID-induced ulcers. Patients with heart disease who are taking aspirin for prevention of heart attacks also are at risk, and the risk of bleeding ulcers doubles if aspirin is combined with other NSAIDs. How do NSAIDs work, and how do they cause stomach problems?

What are the long-term effects of NSAIDs on the stomach?

Approximately 15% of patients on long-term treatment with NSAIDs develop a peptic ulcer (ulceration of the stomach or duodenum). Even though many of these patients with ulcers do not have symptoms and are unaware of their ulcers, they are at risk of developing serious ulcer complications, such as bleeding or perforation of the stomach.